ProtectR® Shipping Tubes


ProtectR® Dry Ice Tubes

Samples of proteins, other biological molecules, and cell cultures are commonly shipped and stored on dry ice, putting them at risk of acidification by up to 2.5 pH units. In standard centrifuge tubes, CO₂ vapor from dry ice enters the tube headspace and causes a significant drop in the pH of the sample.

Even in short term storage conditions, samples may become acidified. This acidification can affect the integrity and reproducibility of samples, and may result in a loss of protein activity. Labcon ProtectR® Tubes prevent CO₂ acidification when storing or shipping samples with Dry Ice.


Full Protection from pH Damage

Most international and domestic carriers now require adherence to the IATA standards for all biological substance shipments. IATA 95 kPa certification ensures containers are leak-resistant under differential pressure conditions such as in air transport. This certification requires containers to prove capable of withstanding, without leakage, an internal pressure producing a pressure differential of not less than 95 kPa (0.95 bar, 13.8 psi).

ProtectR® tubes are the ideal vessel for primary and secondary sample containment. Samples are shipped on dry ice in a variety of volumes. When shipped in standard or small volume tubes, samples are at risk of acidifcation. ProtectR® tubes can be used as a secondary shipping tube for multiple small volume tubes. With their airtight, leak-resistant secure seal, ProtectR® tubes provide a protective barrier against CO₂ exposure, safeguarding the sample inside from costly damage. Only ProtectR® tubes ensure consistent sample integrity and protein activity across experiments. Even if samples are delayed during shipping, they will not become compromised, saving time and money.

ProtectR features

ProtectR® tubes feature our Patented labeling spot that helps to reduce smearing of lab markers at the same time it protects sample labeling from damage during storage or procedures. ProtectR® tubes are available in our exclusive 10 tube IntegraPack® packaging. And like all our sterile products we only use medical grade packaging and sterilize following a validated ISO 11137 medical grade method to an SAL of 10-6.

Endotoxin Endotoxin Free (Non pyrogenic)
Product samples are exposed to endotoxin-free water and the resulting extraction fluid is tested for contamination using the kinetic turbidimetric Limulus Amoebocyte Lysate (LAL) assay protocol and USP guidelines. All products tested must display less than 0.05 EU/ml to be certified free of endotoxin.
RNase/DNase Nuclease Free (RNase/DNase)
Product samples are exposed to nuclease-free water and the resulting extraction fluid is tested for nuclease activity on commercially available 7.5 kb Poly(A) tailed RNA (1µg) and HindIII-digested DNA (1µg) with a one hour 37°C incubation in appropriate buffers. Results are visualized on an agarose gel with appropriate positive and negative controls. Extraction fluid samples must show no degradation of the nucleic acids by the extraction fluid has occurred for the product to be certified as RNase-free and DNase-free
ATP Adenosine Triphosphate (ATP)
Product sample surfaces are tested for the presence of adenosine triphosphate (ATP) using a controlled bioluminescence reaction to detect contamination. Luminescence data is compared to results generated by ATP-free surfaces and surfaces with known amounts of ATP as a positive control. The relative light units result must indicate less than 2 X 10-12 mg/µl of ATP for the product to be certified as ATP free.
USP Metals Heavy Metals Free
Heavy metals have been tested for using the prescribed USP method and confirmed to have levels lower than 1 part per million (1ppm)
Sterilization Validated Sterilization
Labcon products are sterilized by radiation sterilization within a dose range of 12-35 kGy. The dose range necessary for the stated sterility assurance level is continuously audited through quarterly bio-burden and sterility validation studies performed according to the ANSI/AAMI/ISO 11137 standard by an independent laboratory. This dosage is sufficient to guarantee a sterility assurance level of 10-6.
Products are pressure and temperature tested to confirm that they are suitable for use as shipping tubes. This work was performed by a third party laboratory. Tubes were filled with a glycerol-water mix and incubated at 25°C in a vacuum chamber at -95kPa for 30 minutes, with no leakage of liquid content observed. Tubes were then incubated at -40°C for two hours at the -95kPA differential, again with no leaking of liquid contents observed. The tubes were then incubated at +55°C for two hours at the -95kPA differential, again with no leaking observed.
BSE/TSE Bovine Spongiform Encephalopathy-Transmissible Spongiform Encephalopathy
These products contain resins that are processed under conditions proven to exceed the European Union standard as listed in the 22nd Commission Directive EC 98/16/EC of March 5th, 1998 as annexed to council Directive EC 76/768/EEC and further Amendment 419 Annex II of 12 June 2001.
USP Medical Grade (USP)
U.S Pharmacoepia Methods and Guidelines (U.S.P Class VI) are used if applicable. We only use medical grade resins and pre-test all resins for contaminants prior to use. Resins are compliant with FDA CFR title 21-177.1520, 178.3295, 178.3297.
Prop 65 California Prop 65
No Labcon manufactured disposables contain any of the “listed chemicals” as referenced in the California Safe Drinking Water and Toxic Enforcement Act of 1986, (Prop 65) as revised May 25, 2018.
Phthalates Phthalates & Oleamide
All our resins are medical grade and are certified free of Bisphenol A (BPA), Oleamide, DiHEMDA, and Phthalates.
SVHC Substances of Very High Concern & REACH
All Labcon products are compliant with RoHS Directive 2002/95/EC/-2011/65-2015/863, are free of Substances of Very High Concern (SVHC), and are EU REACH Regulation (EC) No 1907/2006 compliant.
USA Origin
These products are Made in USA and all components meet the requirements for US origin under the NAFTA agreement.
FDA U.S. FDA Registered
Labcon is a U.S. FDA registered medical device manufacturer. Our facility is registered by the U.S. government to comply with CFR21 GMP regulations for manufacturing medical devices.
CE CE Compliant
As applicable Labcon products meet the requirements for CE marking under regulation 2017/746.
ISO ISO 9001 Quality Registration
Labcon has been registered to the ISO 9001 quality management system standar since 1997 and maintains registration to ISO 9001:2015.
Material 100% Virgin Polypropylene
Grade Medical
Rating USP Class VI
Colors Natural (Clear) with Yellow Green color cap
Length Various
Fits Most popular centrifuges
Approved Use Medical, Research, Industrial, Food & Beverage
Lot Expiration 4 years
Sterile Expiration 3 years

The unique IntegraPACK® is available for uses that demand a clean product. Each package includes 5 sets of 10 tubes. The tubes are oriented in the package for ease of use. Available sterilized by irradiation.

FDA Registered

Labcon is registered by the U.S. Food and Drug Administration to manufacture medical devices.

Medical Grade Resins

Only 100% Medical Grade virgin polypropylene resins are used in ProtectR® tubes. No recycled plastics or commodity grade resins.

Lab Tested

ProtectR® tubes were developed using our own in-house laboratory and tested in air shipment.

Certified Quality

Our products are made to ISO standards and we are audited every 6 months to ensure you continous quality.

Certificates Online

Real test certificates are available by lot for ProtectR® tubes for you to download from the certificates page.

Sustainability Built In

ProtectR® tubes are designed from the beginning with sustainability in mind. Beyond simple recycling to real solutions.